Locke Health uses a boutique “capital + execution” approach to support the founder and investor community for the future of healthcare.
Launched
Based in
Focus
Partnership with
Locke Health backs exceptional founders solving healthcare’s hardest problems. We invest in early-stage teams modernizing care delivery, clinical operations, and the way health data creates value across ecosystems.
Healthcare is too important to stay the same. We partner with companies that turn complexity into clarity and deliver what matters most.
A boutique approach built to support the founder and investor community for the future of healthcare.
A $25mm fund investing in early-stage healthcare startups, with the goal of being a high-conviction, founder-aligned capital partner from day one. Our mission: appropriately capitalize the Midwest region and support the next generation of game-changing founders in the healthcare & well-being ecosystem.
About the fund →Built for execution, helping companies accelerate on strategic, market-ready partnerships and the operational work that turns strong ideas into real action. The fund + advisory model lets us show up with more than capital, through hands-on help that early-stage teams often need most.
Meet the advisory team →Locke Health Advisory lead deals from start to finish, acting as true partners throughout the entire process. With deep expertise in enterprise healthcare sales and backed by an average of 20 years of experience per team member, we deliver results with precision and insight. Our team stays fully engaged until the work is complete, allowing founders to remain focused on building and scaling their products. Unlike traditional advisors, our operating partners actively drive revenue within portfolio companies, working hands-on where it matters most.
years of experience, on average, per team member
Our portfolio is a testament to our commitment to investing in innovative, high-growth companies. We partner with visionary founders and investors who are shaping the future of healthcare.

AI-powered surgical intelligence platform optimizing workflows, utilization, and revenue.

Empowering a higher standard for front-line healthcare workers and their well-being.

Pre-services consumer billing platform, simplifying the patient financial experience.

Data accessibility company purpose built for healthcare interoperability at scale.

Grid-scale energy infrastructure enabling AI and healthcare industry growth.
Intelligent financial operating system helping physician practices improve cash flow.
Four steps from your first introduction to a final investment decision.
This is our first chance to meet your company. Use the Get in Touch button to send us your name, company, and details.
Once you fill out our contact form, your information will be reviewed by our team. If you fit our investment criteria, we will start with an introductory phone call to learn more about your company.
As a co-investment fund, we partner with other institutional investors. If you already have an institutional investor committed to your round, we would like to connect. If you don’t, we explore the interest of our network.
After about 6–8 weeks, the final investment decisions are made by the Locke Health investment committee.






Locke Health operates as a specialized healthcare investment and management arm within the broader Locke Capital ecosystem. This strategic structure allows us to focus exclusively and independently on healthcare opportunities while leveraging the resources, infrastructure, and institutional knowledge of our parent organization.

Send us your name, company, and a few details. We respond within one week.



Locke Health backs exceptional founders solving healthcare's hardest problems. We invest in early-stage teams modernizing care delivery, clinical operations, and the way health data creates value across ecosystems. Healthcare is too important to stay the same. We partner with companies that turn complexity into clarity and deliver what matters most: better access, better outcomes, and better economics.
Locke Health Advisory lead deals from start to finish, acting as true partners throughout the entire process. With deep expertise in enterprise healthcare sales and backed by an average of 20 years of experience per team member, we deliver results with precision and insight. Our team stays fully engaged until the work is complete, allowing founders to remain focused on building and scaling their products. Unlike traditional advisors, our operating partners actively drive revenue within portfolio companies, working hands-on where it matters most.
Locke Health uses a boutique "capital + execution" approach to support the founder and investor community for the future of healthcare.